HYDERABAD, India and TORONTO, Oct. 21, 2020 /PRNewswire/ — Excelra, a leading global Data & Analytics organization, today announced that it has licensed its Global Online Structure Activity Relationship Database (GOSTAR) to Cyclica Inc., a leading biotechnology company whose AI-augmented integrated platform enables multi-objective, polypharmacology-informed design of drug molecules

GOSTAR is the largest online structure activity relationship database comprising of over 5.5 million small molecules and their associated chemical, biological and pharmacological properties. The database is manually curated by our scientific team who excerpt and enrich datasets from functional assays, in vitro and in vivo studies. A variety of small molecule activities encompassing SAR, physicochemical, metabolic, ADME and toxicological profiles are captured and structured into a relational database. GOSTAR ultimately equips researchers with insights to generate novel ideas in drug design in the early as well as optimization stages of drug discovery

Dr. Raveendra Dayam, Director, Chemistry Services, Excelra said: “GOSTAR provides access to more than 28 million experimentally determined quantitative interactions between small molecules and the vast druggable target space. Insights derived from these interactions complement Cyclica’s polypharmacology approach in novel compound drug discovery. GOSTAR is a rich qualitative and quantitative dataset that is applied by many AI/ML companies and we are excited that the data will support Cyclica with its predictive analytics.”The breadth of data provided by GOSTAR will broaden the domain of applicability of Cyclica’s models, as Dr. Stephen MacKinnon, VP of R&D at Cyclica indicates: “The collaboration with GOSTAR strengthens Cyclica’s training data for our platform models by allowing Cyclica to annotate our proteome screening data, thus enhancing our predicted interaction capabilities. This will have a direct impact on the development of more precise and efficacious medicines for patients in need.”About CyclicaCyclica is the first company to approach polypharmacology with a structure-based, AI-augmented in silico discovery platform, centered on ‘Ligand Design’ and ‘Ligand Express’. Powered by MatchMaker™, a proprietary deep learning proteome screening technology, and POEM™, an innovative supervised learning technology for predicting molecular properties. To know more, visit www.cyclicarx.comAbout Excelra:Excelra’s data and analytics solutions empower innovation in life sciences from molecule to market. The Excelra Edge comes from a seamless amalgamation of proprietary data assets, domain expertise and data science to accelerate drug discovery and development. To know more, visit www.excelra.comLogo: https://mma.prnewswire.com/media/692189/Excelra_Logo.jpg PWRPWR

Confusing numbers and scanty information on how effective curfews and lockdowns have been in breaking transmission have amplified coordination and planning challenges in Kenyas response to COVID-19. Without accurate data, it is impossible t…

In insistences such as the battle over the Luna, Akhmedov has resorted to extreme legal machinations to subvert the High Courts decision and keep his assets from being seized. …

Freight volumes in the Port of Rotterdam improved in the third quarter after the deep slump caused by the coronavirus pandemic in the first half of the year, Europes largest sea port said on Wednesday. Throughput of agribulk, iron ore, biom…

One can debate on quantum of development in Bihar, but no one can point finger at CM Nitish Kumar on corruption Rajnath Singh….

West Bengal Congress president Adhir Ranjan Chowdhury on Wednesday expressed doubt if the Calcutta High Court order making all community puja pandals as no-entry zone will be enforced in letter and spirit by the state administration. He sai…

Realty major DLFs rental arm has given on lease 7.7 lakh sq ft office space to Standard Chartered GBS in an upcoming commercial tower in Chennai to be constructed at a cost of around Rs 450 crore, a senior company official said on Wednesday…

Source: https://www.devdiscourse.com/article/business/1268754-cyclica-to-use-excelras-gostar-database-to-develop-ai-ml-based-deep-learning-algorithm-for-drug-target-identification

Artificial intelligence, Excelra, Machine learning, Deep learning, Biological target, Drug discovery, Database

World news – GB – Cyclica to use Excelra’s GOSTAR Database to develop AI & ML based Deep Learning Algorithm for Drug Target Identification | Business

En s’appuyant sur ses expertises dans les domaines du digital, des technologies et des process , CSS Engineering vous accompagne dans vos chantiers de transformation les plus ambitieux et vous aide à faire émerger de nouvelles idées, de nouvelles offres, de nouveaux modes de collaboration, de nouvelles manières de produire et de vendre.

CSS Engineering s’implique dans les projets de chaque client comme si c’était les siens. Nous croyons qu’une société de conseil devrait être plus que d’un conseiller. Nous nous mettons à la place de nos clients, pour aligner nos incitations à leurs objectifs, et collaborer pour débloquer le plein potentiel de leur entreprise. Cela établit des relations profondes et agréables.

Nos services:

  1. Création des sites web professionnels
  2. Hébergement web haute performance et illimité
  3. Vente et installation des caméras de vidéo surveillance
  4. Vente et installation des système de sécurité et d’alarme
  5. E-Marketing

Toutes nos réalisations ici https://www.css-engineering.com/en/works/

LEAVE A REPLY

Please enter your comment!
Please enter your name here